BDBM50008746 CHEMBL3236343

SMILES O=C(NCc1noc(n1)-c1nn(CCn2ccnc2)c2ccccc12)c1ccccc1

InChI Key InChIKey=PYIJFQHNPPKBFX-UHFFFAOYSA-N

Data  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008746   

TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of human Nav1.2 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of human Nav1.2 assessed as 10 Hz block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50008746(CHEMBL3236343)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of human Nav1.2 assessed as inactivated-state block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed